Item Type | Name |
Concept
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Islets of Langerhans Transplantation
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Academic Article
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Sequence and functional characterization of a third inositol trisphosphate receptor subtype, IP3R-3, expressed in pancreatic islets, kidney, gastrointestinal tract, and other tissues.
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Academic Article
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Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance.
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Academic Article
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Chromosomal assignment and tissue distribution of novel expressed sequence tags from a human pancreatic islet cDNA library.
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Academic Article
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NIDDM is associated with loss of pancreatic beta-cell L-type Ca2+ channel activity.
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Academic Article
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Rat inwardly rectifying potassium channel Kir6.2: cloning electrophysiological characterization, and decreased expression in pancreatic islets of male Zucker diabetic fatty rats.
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Academic Article
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Cloning and characterization of exodus, a novel beta-chemokine.
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Academic Article
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Changes in pancreatic islet glucokinase and hexokinase activities with increasing age, obesity, and the onset of diabetes.
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Academic Article
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Hepatic function in a family with a nonsense mutation (R154X) in the hepatocyte nuclear factor-4alpha/MODY1 gene.
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Academic Article
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Maturity onset diabetes of the young (MODY).
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Academic Article
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An approach for identifying simple sequence repeat DNA polymorphisms near cloned cDNAs and genes. Linkage studies of the islet amyloid polypeptide/amylin and liver glycogen synthase genes and NIDDM.
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Academic Article
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Linkage studies in NIDDM with markers near the sulphonylurea receptor gene.
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Academic Article
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Abnormal nephron development associated with a frameshift mutation in the transcription factor hepatocyte nuclear factor-1 beta.
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Academic Article
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beta-cell transcription factors and diabetes: no evidence for diabetes-associated mutations in the gene encoding the basic helix-loop-helix transcription factor neurogenic differentiation 4 (NEUROD4) in Japanese patients with MODY.
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Academic Article
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Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young.
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Academic Article
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Functional properties of the R154X HNF-4alpha protein generated by a mutation associated with maturity-onset diabetes of the young, type 1.
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Academic Article
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Beta-cell transcription factors and diabetes: no evidence for diabetes-associated mutations in the hepatocyte nuclear factor-3beta gene (HNF3B) in Japanese patients with maturity-onset diabetes of the young.
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Academic Article
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Calpains play a role in insulin secretion and action.
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Academic Article
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Diabetes mellitus and genetically programmed defects in beta-cell function.
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Academic Article
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A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin.
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Academic Article
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Control of pancreas and liver gene expression by HNF transcription factors.
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Academic Article
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Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells.
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Academic Article
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RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets.
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Academic Article
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Imaging Beta cell development in real-time using pancreatic explants from mice with green fluorescent protein-labeled pancreatic Beta cells.
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Academic Article
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Glycemic control promotes pancreatic beta-cell regeneration in streptozotocin-induced diabetic mice.
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Academic Article
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Seeing is believing: how the MIP-luc mouse can advance the field of islet transplantation and ß-cell regeneration.
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Academic Article
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Compensation in pancreatic beta-cell function in subjects with glucokinase mutations.
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Academic Article
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Localization of inositol trisphosphate receptor subtype 3 to insulin and somatostatin secretory granules and regulation of expression in islets and insulinoma cells.
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Academic Article
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Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat.
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Academic Article
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A molecular inventory of human pancreatic islets: sequence analysis of 1000 cDNA clones.
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Academic Article
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No evidence for mutations in a putative beta-cell ATP-sensitive K+ channel subunit in MODY, NIDDM, or GDM.
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Academic Article
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Expression of calcium channel mRNAs in rat pancreatic islets and downregulation after glucose infusion.
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Academic Article
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Maturity-onset diabetes of the young.
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Academic Article
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Organization of the human GLUT2 (pancreatic beta-cell and hepatocyte) glucose transporter gene.
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Academic Article
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Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes.
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Academic Article
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Cloning of rat KATP-2 channel and decreased expression in pancreatic islets of male Zucker diabetic fatty rats.
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Academic Article
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5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways.
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Academic Article
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Three Strikes and You're Cured.
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Academic Article
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Creation of an inositol 1,4,5-trisphosphate-sensitive Ca2+ store in secretory granules of insulin-producing cells.
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Academic Article
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Molecular model of human beta-cell glucokinase built by analogy to the crystal structure of yeast hexokinase B.
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Academic Article
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Human pancreatic beta-cell glucokinase: cDNA sequence and localization of the polymorphic gene to chromosome 7, band p 13.
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Academic Article
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Intrapancreatic delivery of human umbilical cord blood aldehyde dehydrogenase-producing cells promotes islet regeneration.
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Grant
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Diabetes Research and Training Center
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Grant
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Transcriptional Regulatory Networks in Pancreatic Islets
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